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Domesticate is a 11 letter word which starts with the letter D and ends with the letter E for which we found 3 definitions.

(a.) To make domestic; to habituate to home life; as to domesticate one's self.
(a.) To cause to be as it were of one's family or country; as to domesticate a foreign custom or word.
(a.) To tame or reclaim from a wild state; as to domesticate wild animals; to domesticate a plant.
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