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exacerbation

Exacerbation is a 12 letter word which starts with the letter E and ends with the letter N for which we found 2 definitions.

Definition
(n.) The act rendering more violent or bitter; the state of being exacerbated or intensified in violence or malignity; as exacerbation of passion.
(n.) A periodical increase of violence in a disease as in remittent or continious fever; an increased energy of diseased and painful action.
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